It has been my observation that when someone has an ascendant in Cancer, all things equal, the person tends to be cautious and security conscious.
And apparently I missed the obvious. A client with Ascendant in Cancer kept saying that she’s almost psychic. I attributed that to her Moon (in Leo) on the 3rd cusp in the Placidus House system, Uranus conjunct Pluto in 3rd. And I forgot about ASC in Cancer!